Erythema nodosum - U-Erythema Nodosum
https://en.wikipedia.org/wiki/Erythema_nodosum
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Kubonakala njengeqhubu elibuhlungu erythematous emlenzeni.


U-Erythema Nodosum (Erythema nodosum) kuSifo Sofuba. Isifo sofuba singenye yezimbangela ezibalulekile U-Erythema Nodosum (Erythema nodosum)
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References
Erythema Nodosum: A Practical Approach and Diagnostic Algorithm 33683567 NIH
Erythema nodosum wuhlobo oluvame kakhulu lwe-panniculitis, olubonakala ngamaqhuqhuva abomvu abuhlungu, atholakala kakhulu emilenzeni engezansi. Imbangela yayo ayikaziwa, kodwa ibonakala iwumphumela wokusabela okuyihaba ezibangeni ezihlukahlukene. Nakuba imvelaphi yayo ivame ukungaqiniseki, kubalulekile ukukhipha ezinye izimo ezingaphansi ngaphambi kokuxilonga primary erythema nodosum. Kungabonisa ukuqala kwezifo zesistimu ezifana nezifo, ukuvuvukala, umdlavuza, noma ukusabela emithini. Izibangeli ezijwayelekile zifaka okuthi strep infections, tuberculosis, sarcoidosis, Behçet's disease, inflammatory bowel disease, certain medications, pregnancy.
Erythema nodosum is the most common form of panniculitis and is characterized by tender erythematous nodules mainly in the lower limbs on the pretibial area. The exact cause of erythema nodosum is unknown, although it appears to be a hypersensitivity response to a variety of antigenic stimuli. Although the etiology is mostly idiopathic, ruling out an underlying disease is imperative before diagnosing primary erythema nodosum. Erythema nodosum can be the first sign of a systemic disease that is triggered by a large group of processes, such as infections, inflammatory diseases, neoplasia, and/or drugs. The most common identifiable causes are streptococcal infections, primary tuberculosis, sarcoidosis, Behçet disease, inflammatory bowel disease, drugs, and pregnancy.
Panniculitis in Children 34449587 NIH
Panniculitis isho isethi ehlukahlukene yezimo zokuvuvukala ezithinta izicubu ezinamafutha ngaphansi kwesikhumba. Lezi zimo azivamile ezinganeni. I- Panniculitis ingaba yinkinga enkulu esimweni sohlelo noma ukusabela okwesibili ezicini ezifana nokutheleleka, ukulimala, noma imithi ethile. Kungakhathaliseki ukuthi iyini imbangela, izinhlobo eziningi ze- panniculitis zibonisa izimpawu ezifanayo, kuhlanganise namaqhubu abuhlungu, abomvu ngaphansi kwesikhumba.
Panniculitides form a heterogenous group of inflammatory diseases that involve the subcutaneous adipose tissue. These disorders are rare in children and have many aetiologies. As in adults, the panniculitis can be the primary process in a systemic disorder or a secondary process that results from infection, trauma or exposure to medication. Some types of panniculitis are seen more commonly or exclusively in children, and several new entities have been described in recent years. Most types of panniculitis have the same clinical presentation (regardless of the aetiology), with tender, erythematous subcutaneous nodules.
Erythema nodosum - a review of an uncommon panniculitis 24746312Panniculitis , ukuvuvukala kongqimba lwamafutha ngaphansi kwesikhumba, yisimo esingavamile ngokuvamile esibonakala njengamaqhuqhuva avuvukele. I- Erythema nodosum (EN) iwuhlobo oluvame kakhulu, ngokuvamile olubangelwa izici ezihlukahlukene. Nakuba cishe amaphesenti angu-55 amacala engenaso isizathu esicacile, izimbangela ezivamile zihlanganisa izifo, imithi, izifo ezithile ezifana ne-sarcoidosis kanye nesifo samathumbu esivuthayo, ukukhulelwa, nomdlavuza. I-EN ivamise ukuvela entsheni nasebancane abadala, kaningi kwabesifazane. Ngokuvamile kwandulelwa umuzwa ojwayelekile wokugula othatha isonto elilodwa kuya kwamathathu, onezimpawu ezifana nomkhuhlane kanye nezinkinga zokuphefumula. Khona-ke, kuvela amaqhuqhuva abomvu, ngokuvamile ezinhlangothini zangaphandle zezingalo nemilenze, okubangela ubuhlungu. Imbangela eqondile ye-EN ayiqondwa ngokugcwele, kodwa kukholakala ukuthi ihlanganisa ama-immune complexes emithanjeni yegazi emincane yongqimba lwamafutha, okuholela ekuvuvukeni. Ngokuvamile, i-biopsy ibonisa ukuvuvukala kungqimba lwamafutha ngaphandle kokulimala emithanjeni yegazi. Ngisho nangaphandle kokwelashwa okuqondile kwembangela ewumsuka, i-EN ivame ukuzixazulula ngokwayo. Ngakho-ke, iziguli eziningi zidinga ukunakekelwa okusekela kuphela izimpawu zazo.
Panniculitis, an inflammation of the fat layer under the skin, is a rare condition usually showing up as swollen nodules or patches. Erythema nodosum (EN) is the most common type, often triggered by various factors. While around 55% of cases have no clear cause, common triggers include infections, medications, certain diseases like sarcoidosis and inflammatory bowel disease, pregnancy, and cancer. EN usually appears in teens and young adults, more often in females. It's often preceded by a general feeling of illness lasting one to three weeks, with symptoms like fever and upper respiratory issues. Then, red nodules appear, usually on the outer sides of arms and legs, causing pain. EN's exact cause isn't fully understood, but it's believed to involve immune complexes in small blood vessels of the fat layer, leading to inflammation. Typically, a biopsy shows inflammation in the fat layer without damage to blood vessels. Even without specific treatment for the underlying cause, EN often resolves on its own. So, most patients need only supportive care for their symptoms.
I-Erythema nodosum itholakala emtholampilo. I-biopsy ingathathwa futhi ihlolwe nge-microscope ukuze kuqinisekiswe ukuxilongwa okungaqinisekile. I-X-ray yesifuba kufanele yenziwe ukuze kukhishwe izifo zamaphaphu, ikakhulukazi i-sarcoidosis nesifo sofuba.